By Plamen Demirev,Todd R. Sandrin
In the final region century, advances in mass spectrometry (MS) were on the vanguard of efforts to map advanced organic structures together with the human metabolome, proteome, and microbiome. All of those advancements have allowed MS to develop into a well-established molecular point know-how for microorganism characterization. MS has validated its massive virtue as a fast, exact, and inexpensive technique for microorganism identity, in comparison to traditional phenotypic options. within the final a number of years, purposes of MS for microorganism characterization in learn, scientific microbiology, counter-bioterrorism, meals defense, and environmental tracking were documented in millions of courses. Regulatory our bodies in Europe, the united states, and somewhere else have authorized MS-based assays for infectious illness diagnostics. As of mid-2015, greater than 3300 advertisement MS structures for microorganism id were deployed world wide in hospitals and scientific labs.
While prior paintings has lined broader techniques in utilizing MS to represent microorganisms on the species point or above, this publication specializes in strain-level and subtyping functions. In twelve person chapters, innovators, leaders and practitioners within the box from world wide have contributed to a complete assessment of present and next-generation methods for MS-based microbial characterization on the subspecies and pressure degrees. Chapters contain up to date reference lists in addition to web-links to databases, urged software program, and different necessary tools.
The emergence of latest, antibiotic-resistant lines of human or animal pathogens is of remarkable challenge not just to the clinical and scientific groups, yet to most of the people besides. advancements of novel MS-based assays for speedy identity of traces of antibiotic-resistant microorganisms are reviewed within the ebook in addition. Microbiologists, bioanalytical scientists, infectious disorder experts, medical laboratory and public health and wellbeing practitioners in addition to researchers in universities, hospitals, executive labs, and the pharmaceutical and biotechnology industries will locate this publication to be a well timed and helpful resource.
Read or Download Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance PDF
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